Natalie Portman denies the rumor

Natalie Portman is fed up with the Sean Penn hookup rumors. "Sean Penn is a friend and colleague," the actress, 27, tells Usmagazine.com. "The reports that we are romantically involved are completely untrue." Tabloid Star magazine claimed that Penn, 48 -- who recently filed for legal separation from his wife of 13 years, Robin Wright Penn -- and Portman were "making out" at West Hollywood's Sunset Tower Hotel in March. Portman continues: "I normally do not respond to rumors about my private life, however, this repeatedly fabricated story has forced me to do so."

(Source: usmagazine.com)