Surrounded by close friends and family, the pair became husband and wife after days of pre-wedding celebrations leading up to the event.
"It was a fantasy," Biel, 30, tells PEOPLE of the nuptials, which will be featured exclusively in this week's PEOPLE magazine, debuting online Wednesday.
Italy - a special location for the couple partly because of their love for its food and wine - served as the perfect backdrop for the festivities, which began earlier in the week.
"It's great to be married, the ceremony was beautiful and it was so special to be surrounded by our family and friends," the couple told PEOPLE in an exclusive statement Friday.
The newlyweds were spotted at the airport on Sunday for their first public outing since the big wedding (he was sporting a gold band). It's presumed the Mr. and Mrs. were heading off on their honeymoon.